For example, a possible result may be a 1 in 50 or 1 in 700 chance that the baby has trisomy 21. In both "screen negative" and "screen positive" situations, the report will also give you a specific chance that your baby has trisomy 21. Some individuals will get a “ screen positive” result, which means that there is a have a higher chance to have a baby with trisomy 21 or trisomy 18. If your report does not include information about trisomy 18, you can assume you have a "screen negative" result for this chromosome difference as well. This means that you have a lower chance to have a baby with trisomy 21. When you receive your STS report, it will most likely say that you have a result that is “ screen negative”. Talk to your provider about how they plan to share these results with you. Note that there may be a delay between the time that the report is sent to your provider and the time when the provider receives it. The STS result will be shared with your health-care provider within approximately 5 working days. You will be asked about your racial identity, diabetes status, smoking history in the pregnancy, weight and whether the pregnancy happened through in vitro fertilization. Your health-care provider will ask you some questions about you that improve the accuracy of test. unconjugated estriol (uE3) – a form of estrogen that increases during pregnancy.inhibin-A – a protein made by the baby and the placenta.alpha-fetoprotein (AFP) – a protein made by the baby's liver.human chorionic gonadotropin (hCG) – a hormone made by the placenta during pregnancy.The blood test for STS will measure the amount of 4 different hormones (or chemicals) that are present in your blood: If the pregnancy happened through IVF, it is the age of the egg that is taken into account (whether it is your own or a donor egg). There is a higher chance for chromosome differences like trisomy 21 and trisomy 18 as the age of the pregnant individual increases. The test will combine all the information below to tell you about the chance to have a baby with trisomy 21 (Down syndrome) and trisomy 18. Even though an ultrasound is not necessary for this test, a regular ultrasound improves the accuracy of STS and how the pregnancy is looked after. STS is not recommended for pregnancies that had PGT-A, since PGT-A is considered to be a better screen. PGT-A is a highly effective screen, which means it can pick up most embryos with trisomy 21 and trisomy 18. PGT-A involves screening embryos for chromosome differences, including trisomy 21 and trisomy 18. the pregnancy happened after in vitro fertilization (IVF) and the embryos were screened through Preimplantation Genetic Testing (PGT-A) during that process.there is more than one baby (twins, triplets, quadruplets etc).you have already received a "low risk" result from Non-Invasive Prenatal Testing (NIPT), or you are waiting for your NIPT results.Consider having enhanced First Trimester Screening (eFTS) instead of STS. you are in the first trimester and have access to a nuchal translucency ultrasound.
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